Rna Aptamers Targeting the Cell Death Inhibitor Ced-9 Induce Cell Killing in C. Elegans*

RNA APTAMERS TARGETING THE CELL DEATH INHIBITOR CED-9 INDUCE CELL KILLING IN C. ELEGANS* Chonglin Yang, Nieng Yan, Jay Parish, Xiaochen Wang, Yigong Shi and Ding Xue From the Department of MCD Biology, University of Colorado, Boulder, Colorado 80309, Department of Molecular Biology, University of Princeton, Princeton, NJ 08544 Current address: Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143-0725 Running title: CED-9 aptamers induce apoptosis Address correspondence to: Dr. Ding Xue, Department of MCD Biology, University of Colorado, Boulder, Colorado 80309, Tel. 303 492-0271; Fax: 303 492-7744; E-Mail: [email protected]